Yoga for Immunity is an evidence-based practice that significantly modulates immune function through multiple physiological pathways. A 2025 systematic review of 26 RCTs found that practising yoga (at least twice weekly for 8 weeks or longer) improves immune function across several autoimmune disorders, including multiple sclerosis, rheumatoid arthritis, ankylosing spondylitis, and inflammatory bowel disease.
Key Research Findings
- Inflammatory markers: A 2025 meta-analysis of 7 RCTs (502 IBD patients) found that yoga-based interventions significantly reduced inflammatory markers (CRP, FCP) while improving quality of life and reducing anxiety, depression, and perceived stress.
- Natural killer cell activity: A 2025 crossover study of 7 healthy men found that 30 minutes of yoga after intense exercise significantly prevented a decline in NK cell activity (P < 0.05), with enhanced parasympathetic nerve activity accounting for the effect.
- Gene expression: A 2025 systematic review of 11 RCTs (700+ adults) found that yoga consistently downregulated pro-inflammatory genes (IL-6, TNF-α, NF-κB) across multiple studies, while upregulating anti-inflammatory and immunoregulatory genes.
How Yoga Boosts Immunity
- Downregulates pro-inflammatory cytokines (IL-6, TNF-α) through reduced inflammatory gene expression
- Enhances parasympathetic nervous system activity, which supports immune regulation
- Reduces cortisol and psychological stress, both of which suppress immune function
- Modulates gut-brain axis activity, which influences systemic inflammation
For optimal immune benefits, practice 2-3 sessions weekly (45-60 minutes) for at least 8 weeks. Yoga is safe as an adjunct to conventional medical treatment for autoimmune conditions. Always consult a healthcare provider before beginning any new exercise regimen, especially if you have existing medical conditions.





